To systematically evaluate the correlation between tremor severity and three monoaminergic neurotransmitters (dopamine, serotonin, and norepinephrine) in Parkinson’s disease (PD). Methods: Studies analyzing the correlation between PD tremor and these three monoaminergic neurotransmitters were searched, and a meta-analysis was conducted. Results: A total of 26 studies were included, involving 1878 participants. The meta-analysis revealed no correlation between contralateral putamen dopamine function and PD tremor [r=－0.05, 95%CI (－0.13, 0.03), P=0.194]. Subgroup analysis demonstrated a positive correlation between ipsilateral caudate dopamine function and PD tremor in the early stage of the disease (disease duration≤5 years) [r=0.17, 95%CI (0.10, 0.25), P<0.001]. The results of the correlation analysis between raphe nuclei serotonergic function and PD tremor were unstable [random-effects model: r=－0.23, 95% CI (－0.44, 0.02), P=0.067; fixed-effects model: r=－0.14, 95%CI (－0.23, －0.04), P=0.004]. The tracers used in studies investigating the correlation between noradrenergic function and PD tremor varied significantly, so a systematic review was conducted for this part. Conclusion: The relationship between PD tremor and dopaminergic function may be influenced by brain region and disease duration. In the early stage of the disease, ipsilateral caudate dopamine function is positively correlated with PD tremor severity. The relationships between PD tremor and both serotonergic and noradrenergic functions require further investigation, and it is crucial to use consistent and specific tracers.