To observe the clinical efficacy of acupuncture combined with hyperbaric oxygen therapy in the treatment of idiopathic sudden deafness. Methods: Total 80 patients with idiopathic sudden deafness were randomly divided into a control group and a treatment group, with 40 patients in each group. Both groups received integrated traditional Chinese and Western medicine drug treatment, while the treatment group also received acupuncture and hyperbaric oxygen therapy. The average hearing threshold, clinical efficacy, Tinnitus Handicap Inventory (THI), and Tinnitus Evaluation Questionnaire (TEQ) scores before and after treatment were compared between the two groups. Results: The average hearing thresholds of both groups were improved compared to before treatment (P<0.05), and the degree of improvement in the treatment group was superior to that in the control group, with a statistically significant difference (P=0.010). The effective rate was 55.0% in the control group and 77.5% in the treatment group, with the clinical effective rate in the treatment group being higher than that in the control group, and the difference was statistically significant (χ2 =4.530, P= 0.030). There was no statistically significant difference in TEQ and THI scores before and after treatment in the control group, while there was a statistically significant improvement in TEQ and THI scores after treatment in the treatment group (P<0.05). Conclusion: Acupuncture combined with hyperbaric oxygen therapy in the integrated treatment of idiopathic sudden deafness can effectively alleviate tinnitus symptoms, improve hearing levels, and increase the clinical effective rate.