Feasibility and Predictive Factors for Recanalization of Non-Acute Extracranial Internal Carotid Artery Occlusion

Neural Injury and Functional Reconstruction ›› 2022, Vol. 17 ›› Issue (9) : 509-513.

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Neural Injury and Functional Reconstruction ›› 2022, Vol. 17 ›› Issue (9) : 509-513.
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Feasibility and Predictive Factors for Recanalization of Non-Acute Extracranial Internal Carotid Artery Occlusion

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Abstract

To investigate the feasibility of recanalization of non-acute extracranial internal carotid artery occlusion and the factors affecting recanalization, and to establish a model which can predict the probability of failed recanalization. Methods: In this study, 83 consecutive patients who underwent endovascular recanalization for atherosclerotic extracranial internal carotid artery occlusion from January 2015 to September 2021 in our stroke center were enrolled. The potential risk factors of failed recanalization (gender, age, past history, time from onset to recanalization, angle of the occlusion stump of the internal carotid artery, and whether there was ophthalmic artery regurgitation) were analyzed. A Logistic regression analysis of these factors was utilized to establish a model that could predict the ratio of failed recanalization. Results: Among the 83 patients, 48 were successfully recanalized, and the overall success rate of the operation was 57.8% . Multivariate regression analysis showed that the factors associated with failure of recanalization of internal carotid artery occlusion were age (OR=1.159, 95% CI=1.041~1.328), hypertension (OR=6.213, 95% CI= 1.204~46.54), coronary heart disease (OR=0.025, 95% CI=0.001~0.254), diabetes (OR=0.157, 95% CI= 0.014~1.108), obtuse angle of internal cervical occlusion (OR=0.082, 95% CI=0.008~0.550),and absence of ophthalmic artery regurgitation (OR=0.002, 95% CI=0~0.021). The risk factors of Logistic regression analysis were included in the prediction model and the nomogram was drawn. The area under the ROC curve (AUC value) of the model was 0.947(95% CI=0.898~0.996). Conclusion: Endovascular recanalization of non-acute extracranial internal carotid artery occlusion is technically feasible. Male gender, older age, coronary heart disease, obtuse angle of internal cervical occlusion, and absence of ophthalmic artery regurgitation are predictors of failed recanalization.

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internal carotid artery

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Feasibility and Predictive Factors for Recanalization of Non-Acute Extracranial Internal Carotid Artery Occlusion[J]. Neural Injury and Functional Reconstruction. 2022, 17(9): 509-513
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