Abstract
To investigate the feasibility of recanalization of non-acute extracranial internal carotid
artery occlusion and the factors affecting recanalization, and to establish a model which can predict the
probability of failed recanalization. Methods: In this study, 83 consecutive patients who underwent
endovascular recanalization for atherosclerotic extracranial internal carotid artery occlusion from January 2015
to September 2021 in our stroke center were enrolled. The potential risk factors of failed recanalization (gender,
age, past history, time from onset to recanalization, angle of the occlusion stump of the internal carotid artery,
and whether there was ophthalmic artery regurgitation) were analyzed. A Logistic regression analysis of these
factors was utilized to establish a model that could predict the ratio of failed recanalization. Results: Among
the 83 patients, 48 were successfully recanalized, and the overall success rate of the operation was 57.8% .
Multivariate regression analysis showed that the factors associated with failure of recanalization of internal
carotid artery occlusion were age (OR=1.159, 95% CI=1.041~1.328), hypertension (OR=6.213, 95% CI= 1.204~46.54), coronary heart disease (OR=0.025, 95% CI=0.001~0.254), diabetes (OR=0.157, 95% CI= 0.014~1.108), obtuse angle of internal cervical occlusion (OR=0.082, 95% CI=0.008~0.550),and absence of
ophthalmic artery regurgitation (OR=0.002, 95% CI=0~0.021). The risk factors of Logistic regression analysis
were included in the prediction model and the nomogram was drawn. The area under the ROC curve (AUC
value) of the model was 0.947(95% CI=0.898~0.996). Conclusion: Endovascular recanalization of non-acute
extracranial internal carotid artery occlusion is technically feasible. Male gender, older age, coronary heart
disease, obtuse angle of internal cervical occlusion, and absence of ophthalmic artery regurgitation are
predictors of failed recanalization.
Key words
internal carotid artery
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Feasibility and Predictive Factors for Recanalization of Non-Acute Extracranial Internal
Carotid Artery Occlusion[J]. Neural Injury and Functional Reconstruction. 2022, 17(9): 509-513
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