To systematically review the efficacy of whole-body vibration (WBV) on motor symptoms of Parkinson's disease (PD). Methods: Databases including PubMed, EMbase, Cochrane library, China's National Knowledge Internet (CNKI), China Biology Medicine (CBM), VIP, and WanFang Data from inception to February 2021 were searched to collect randomized controlled trials (RCTs) on WBV training for patients with PD. Meta-analysis was performed using Review Manager 5.3 software. Results: A total of 8 RCTs involving 255 PD patients (138 experimental group patients and 117 control group patients) were included. The results of Meta-analysis showed that, compared with control conditions, WBV training could significantly improve balance [SMD=0.58, 95% CI (0.07, 1.09), P=0.03] and gait [SMD =－0.48, 95% CI (－0.82, －0.13), P=0.007]. Conclusion: WBV can improve balance and gait in patients with PD, thus improving their quality of life.