Effects of Theta Burst Stimulation Combined with Mirror Therapy on Motor Recovery of Upper Limbs of Patients in Stroke Recovery Period

Neural Injury and Functional Reconstruction ›› 2022, Vol. 17 ›› Issue (12) : 701-704.

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Neural Injury and Functional Reconstruction ›› 2022, Vol. 17 ›› Issue (12) : 701-704.
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Effects of Theta Burst Stimulation Combined with Mirror Therapy on Motor Recovery of Upper Limbs of Patients in Stroke Recovery Period

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Abstract

To investigate the effects of intermittent theta burst stimulation (iTBS) combined with mirror image therapy (MT) on upper limb motor function and daily living ability of patients in stroke recovery period. Methods: Forty-six stroke patients were randomly divided into four groups: control group (n=11), iTBS group (n=12), MT group (n=11) and combination group (n=12). Patients in control group received routine rehabilitation treatment, and patients in treatment groups were additionally treated with iTBS, MT and MT combined with iTBS respectively. All the patients received the therapy 5 days per week for 10 working days. Patients were evaluated before treatment (T0), then immediately (T1), 1 month (T2) and 3 months (T3) after treatment. The evaluation included: National Institutes of Health Stroke Scale (NIHSS), upper limb Fugl-Meyer assessment (UL-FMA), Brunnstrom Scale (BS) and Modified Barthel Index (MBI). Results: On comparison with baseline data, the UL-FMA (proximal), upper extremity BS, NIHSS and MBI scores of the four groups were improved after treatment at each time point (P<0.05). For the UL-FMA (distal) score and hand BS, the combination group increased at T1 (P<0.05), while the other three groups began to increase significantly at T2 (P< 0.05). The UL-FMA (proximal) (T3), upper limb and hand BS (T3) and MBI (T2) in combination group were significantly higher than those in control group (P<0.05) and the upper limb BS (T3) was also significantly higher than that in MT group (P<0.05). The upper limb BS (T3) in iTBS group was higher than that in control group (P<0.05). Conclusion: The combination of iTBS and MT therapy can better promote upper limb motor function and activities of daily living of patients in stroke recovery period.

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stroke

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Effects of Theta Burst Stimulation Combined with Mirror Therapy on Motor Recovery of Upper Limbs of Patients in Stroke Recovery Period[J]. Neural Injury and Functional Reconstruction. 2022, 17(12): 701-704
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