Abstract
To investigate the effects of intermittent theta burst stimulation (iTBS) combined with
mirror image therapy (MT) on upper limb motor function and daily living ability of patients in stroke recovery
period. Methods: Forty-six stroke patients were randomly divided into four groups: control group (n=11), iTBS
group (n=12), MT group (n=11) and combination group (n=12). Patients in control group received routine
rehabilitation treatment, and patients in treatment groups were additionally treated with iTBS, MT and MT
combined with iTBS respectively. All the patients received the therapy 5 days per week for 10 working days.
Patients were evaluated before treatment (T0), then immediately (T1), 1 month (T2) and 3 months (T3) after
treatment. The evaluation included: National Institutes of Health Stroke Scale (NIHSS), upper limb Fugl-Meyer
assessment (UL-FMA), Brunnstrom Scale (BS) and Modified Barthel Index (MBI). Results: On comparison
with baseline data, the UL-FMA (proximal), upper extremity BS, NIHSS and MBI scores of the four groups
were improved after treatment at each time point (P<0.05). For the UL-FMA (distal) score and hand BS, the
combination group increased at T1 (P<0.05), while the other three groups began to increase significantly at T2 (P<
0.05). The UL-FMA (proximal) (T3), upper limb and hand BS (T3) and MBI (T2) in combination group were
significantly higher than those in control group (P<0.05) and the upper limb BS (T3) was also significantly
higher than that in MT group (P<0.05). The upper limb BS (T3) in iTBS group was higher than that in control
group (P<0.05). Conclusion: The combination of iTBS and MT therapy can better promote upper limb motor function and activities of
daily living of patients in stroke recovery period.
Key words
stroke
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Effects of Theta Burst Stimulation Combined with Mirror Therapy on Motor Recovery of
Upper Limbs of Patients in Stroke Recovery Period[J]. Neural Injury and Functional Reconstruction. 2022, 17(12): 701-704
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