To investigate the status of stigma in Parkinson’s Disease (PD) patients and its influencing factors. Methods: A total of 168 PD patients were investigated using a general information questionnaire and the 24-item Stigma Scale for Chronic Illness (SSCI). Results: The total SSCI score among Parkinson’s Disease patients was (57.75±17.59); the internal stigma score was (37.10±12.18), and the external stigma score was (20.74±6.66). The result of regression analysis indicated that the self-care ability, compliance with medication regimen, influence on sexual life, and adherence to subsequent visit were the main influencing factors of stigma in PD patients. Conclusion: PD patients suffer moderate level stigma which mainly manifests as internal stigma.