To observe the effect of Brandt-Daroff exercise combined with Deanxit on residual dizziness (RD) after successful canalith repositioning maneuvers (CRP) in patients with benign paroxysmal positional vertigo (BPPV). Methods: Ninety-six patients with RD after successful CRP were divided into four groups at random with 24 patients per group: the control group (treated with routine medical therapy), the exercise group (treated with Brandt-Daroff exercise), the medication group (treated with Deanxit), and the combination group (treated with Brandt-Daroff exercise combined with Deanxit). Before and after treatment, hospital anxiety and depression scale (HADS), dizziness handicap inventory (DHI), and vestibular symptom index (VSI) were evaluated. Results: No significant difference existed in scores of HADS, VSI, and DHI between each group before treatment (P>0.05). Seven days and 14 days after treatment, HADS, VSI, and DHI scores in the control group were higher than those in the other 3 groups (P<0.05). In the combination group, the above scores were lower than those in the exercise group and medication group (P<0.05). Seven days after treatment, HADS score in the medication group was lower than that in the exercise group (P<0.05); 14 days after treatment, DHI score in the exercise group was lower than that in the medication group (P<0.05). Conclusion: Both Brandt-Daroff exercise and Deanxit could effectively ameliorate RD symptoms in BPPV patients with RD after successful CRP, and the treatment was more effective than single method treatment.