Research Progress on the Pathogenesis of Chronic Fatigue Syndrome Based on Mitochondrial Homeostasis

doi:10.16780/j.cnki.sjssgncj.20241205

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Neural Injury and Functional Reconstruction ›› 0 DOI: 10.16780/j.cnki.sjssgncj.20241205

Research Progress on the Pathogenesis of Chronic Fatigue Syndrome Based on Mitochondrial Homeostasis

ZHU Minghang ¹ , YUAN Zhiying ¹ , FENG Chuwen ^2,3 , QU Yuanyuan ² , LIU Tingting¹ , LU Jing ¹ , SHAO Yuying ² , LI Binbin ² , GUO Shuhao ¹ , CHEN Tao ¹ , YANG Tiansong ^2,3 .

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Abstract

Chronic fatigue syndrome (CFS) is closely related to the imbalance of mitochondrial

homeostasis, and studies have shown that mitochondria in CFS patients or model animals have

abnormalities in morphology and structure, metabolism and quality control, which are closely related to the

occurrence and/or development of CFS. In this paper, we take mitochondrial homeostasis as an entry point

to systematically sort out its influence and role in the pathogenesis of CFS, with a view to providing more

ideas and strategies for the study of potential mechanisms and treatment of chronic fatigue syndrome.

Key words

chronic fatigue syndrome

/ mitochondria / homeostasis

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ZHU Minghang 1 , YUAN Zhiying 1 , FENG Chuwen 2, 3 , QU Yuanyuan 2 , LIU Tingting 1 , LU Jing 1 , SHAO Yuying 2 , LI Binbin 2 , GUO Shuhao 1 , CHEN Tao 1 , YANG Tiansong 2, 3.

Research Progress on the Pathogenesis of Chronic Fatigue Syndrome Based on Mitochondrial Homeostasis

[J]. Neural Injury and Functional Reconstruction. 0 https://doi.org/10.16780/j.cnki.sjssgncj.20241205