To explore the relationship between suicidal ideation and cognitive fusion and experiential avoidance in patients with depressive episodes. Methods: A total of 160 patients with depressive episode were enrolled by random sampling method. The general demographic questionnaire, Beck Suicidal Ideation Scale-Chinese version (BSI-CV), Cognitive Fusion Questionnaire (CFQ), Acceptance and Action Questionnaire-second version (AAQ-II) were used to investigate the relationship between suicidal ideation and cognitive fusion and empirical avoidance. Results: There were significant differences in years of education, occupation, marriage, history of abuse, cognitive fusion and experiential avoidance between patients with and without suicidal ideation (P<0.05). The intensity of suicidal ideation was positively correlated with cognitive fusion(OR=0.287, P<0.05) and experiential avoidance (OR=0.349, P<0.05). For cognitive fusion, the "moderate to strong" "desire to passively attempt suicide" was statistically significantly different from "none" and "weak" (P<0.05). For experiential avoidance, the "moderate to strong" "desire to actively attempt suicide" and "desire to passively attempt suicide" were statistically significantly different from "none" and "weak"(P<0.05). Binary Logistics regression showed that the shorter the years of education, the higher the incidence of suicidal ideation (OR=0.781, 95%CI 0.661～0.922, P=0.004); the higher the experiential avoidance, the higher the incidence of suicidal ideation (OR=1.150, 95% CI 1.055～1.255, P=0.002). Conclusion: Both cognitive fusion and experiential avoidance are positively correlated with the intensity of suicidal ideation in patients with depressive episode, and experiential avoidance is a risk factor for suicidal ideation in patients with depressive episode.