To monitor the inflow and drainage function of meningeal lymphatic vessels (mLVs) in patients with cerebral small vessel disease (CSVD) on the basis of multiple phase dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and to explore the correlation between mLVs and imaging biomarkers as well as clinical features of CSVD. Methods: From March 2021 to August 2022, 120 community volunteers were recruited. MRI data were collected to evaluate imaging biomarkers of CSVD. Sixty-five patients who met the criteria were continuously included and divided into a high total CSVD burden group and a low CSVD burden group according to the total MRI burden. Multiple phase DCE-MRI images (pre-enhancement, enhancement, and end-enhancement) were screened to assess the inflow and drainage functions of mLVs. Univariate and multivariate analyses were used to analyze the correlation between mLVs and imaging biomarkers as well as clinical features of CSVD. Results: The mLV area under the curve (2 830.54 v.s 2 450.87, P=0.032) and peak slope (4.03 v.s 3.40, P=0.049) in the high total CSVD burden group were greater than those in the low CSVD burden group, and there was still a statistical difference after adjusting for confounding factors (P=0.028, P=0.031). Patients with deep white matter hyperintensities had impaired mLVs inflow (P= 0.015) and drainage function (P=0.020), while the inflow (P=0.249) and drainage function (P=0.726) did not significantly change in patients with paraventricular white matter hyperintensities. There was no difference in the function of mLVs among patients with different cognitive and emotional states (P>0.05). Conclusion: Changes in the function of mLVs differ among patients with different imaging markers. In addition, patients with a high total CSVD burden have an increased inflow of mLVs, indicating the involvement of mLVs in the pathogenesis of CSVD.