To explore the correlation and influencing factors of white matter hyperintensity (WMH) in patients with Parkinson's disease (PD) on clinical motor and cognitive impairment. Methods: A total of 125 patients with primary PD were enrolled. The clinical data of motor function and cognitive function were evaluated, and the imaging data (T1, T2 and FLAIR sequences) were collected. According to the score of Fazekas scale, the patients were divided into three groups, including 73 mild WMH group, 32 moderate WMH group and 20 severe WMH group. Spearman correlation analysis and ordered multiple Logistic regression analysis were used to determine the correlation between WMH and motor and cognitive impairment in PD patients, as well as the influencing factors of WMH. Results: Older PD patients with hypertension and diabetes had more severe WMH, and with the increase of WMH, the movement disorders and cognitive disorders of the patients gradually increased. WMH load is closely related to the severity of motor and cognitive impairment in PD patients, especially the impairment of specific cognitive domains (visuospatial, language and executive function). Hypertension, diabetes, and poor executive function are independent risk factors for WMH severity in PD patients. Conclusion: The increase of WMH severity is associated with motor and cognitive impairment in PD patients.