Abstract
To assess therapeutic effect of repetitive transcranial magnetic stimulation (rTMS)
combined with neuromuscular electrical stimulation (NMES) on dysphagia after unilateral stroke. Methods: A
total of 96 patients with poststroke dysphagia were enrolled. They were randomly divided into the (rTMS +
NMES) group, rTMS group, or NMES group (each n=32) and treated respectively with rTMS and NMES, rTMS
and sham NMES, or sham rTMS and NMES. At baseline, 2 weeks after treatment, and 1 month after treatment,
the standardized swallowing assessment (SSA), videofluoroscopic swallow study (VFSS), and Rosenbek’s
penetration aspiration scale (PAS) were used to assess swallowing function. Results: Ninety cases were
enrolled in the analysis. At baseline, 2 weeks after treatment, and 1 month after treatment, SSA score (F(2,86)=
322.85, P<0.001) and PAS score (F(2,86)=482.44, P<0.001) were significantly decreased in all 3 groups. After 2
weeks of treatment, PAS and SSA scores in the (rTMS+NMES) group were lower than that of both the rTMS
group (PSSA=0.031, PPAS=0.000) and NMES group (PSSA=0.007, PPAS=0.001). Conclusion: High frequency rTMS
stimulation followed immediately by NMES therapy in the affected side can significantly improve swallowing
function, and its efficacy is superior to that of rTMS or NMES alone.
Key words
transcranial magnetic stimulation
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Repetitive Transcranial Magnetic Stimulation Combined with Neuromuscular Electrical
Stimulation for Treatment of Poststroke Dysphagia[J]. Neural Injury and Functional Reconstruction. 2021, 16(7): 373-377
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