To explore the effects of lower limb robot rehabilitation on motor function, balance function, and walking ability in hemiplegia patients after stroke. Methods: A total of 80 stroke patients with hemiplegia were randomly divided into the control group and intervention group with 40 cases in each group. Both groups received conventional rehabilitation training, and in addition, the intervention group received lower limb rehabilitation robot training. Fugl-Meyer assessment (FMA), Berg balance scale (BBS), Functional Ambulation Category (FAC), 10 minutes maximum walking speed, modified Barthel index (MBI), and integrated electromyography (iEMG) were used to evaluate the outcome. Results: The scores of BBS, FMA, MBI, and iEMG significantly increased after 12 weeks of treatment in both groups (P=0.000), and the scores were significantly improved in the intervention group compared to the control group (P=0.000). After treatment, the percentage of patients with an FAC score of 3 or higher and the 10 minutes maximum walking speed were better in the intervention group than in the control group. Conclusion: The lower limb rehabilitation robot combined with conventional rehabilitation training is effective in improving the motor function, balance function, and walking ability of stroke patients with hemiplegia.