To observe the effects of repetitive transcranial magnetic stimulation (rTMS) combined with computer-assisted cognitive training on the cognitive function and the ability to perform daily activities (ADL) in patients with post-stroke cognitive impairment (PSCI). Methods: A total of 90 PSCI patients were randomly assigned to the cognitive training group, rTMS group, and combined treatment group with 30 patients per group. The three groups were all treated with basic medication and traditional rehabilitation therapy while the cognitive training group was treated additionally with computer-assisted cognitive training, rTMS group was treated additionally with repetitive transcranial magnetic stimulation, and combined treatment group was treated additionally with rTMS and computer-assisted cognitive training. The Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) were used at pre-therapy and 4 weeks after treatment to assess changes in cognitive function in the three groups, and the Modified Barthel Index (MBI) was used to determine changes in ADL ability. Results: No statistical differences were found between the MMSE, MoCA, and MBI scores of the three groups before treatment (P>0.05)．MMSE, MoCA, and MBI scores improved in all three groups 4 weeks after treatment (P<0.05); furthermore, the MMSE, MoCA, and MBI scores of the combined treatment group were significantly higher than those of the cognitive training group and rTMS group (P<0.05). Conclusion: Computer-assisted cognitive training combined with rTMS can effectively improve cognitive function and ADL ability of stroke patients.