精神分裂症是机制不明的常见重型精神障碍。近年来，大量的自噬与精神分裂症的相关研究提示自 噬可能是精神分裂症病理生理过程的一部分，并且药物、物理、心理等治疗可能通过调控自噬缓解精神病性 症状，使自噬调控成为治疗精神分裂症的新方向。本文综述自噬与精神分裂症发病机制的关系，以及自噬 在精神分裂症治疗方面的研究进展，为精神分裂症的诊疗探索提供新的思路。

Schizophrenia is a common and severe mental disorder with unknown mechanisms. In recent years, a large number of studies on the correlation between autophagy and schizophrenia have suggested that autophagy may be part of the pathophysiological process of schizophrenia. Moreover, treatments such as medication, physics, and psychotherapy may alleviate psychotic symptoms by regulating autophagy, making autophagy regulation a new direction for the treatment of schizophrenia. This paper reviews the relationship between autophagy and the pathogenesis of schizophrenia, as well as advancements in autophagy-related treatments, providing new ideas for the diagnosis and treatment exploration of schizophrenia.