目的：探讨间歇性θ短阵脉冲刺激（intermittent theta-burst stimulation，iTBS）小脑蚓部对脑卒中患者下 肢运动功能障碍的影响。方法：脑卒中后下肢运动障碍患者42例，随机分为iTBS组21例与对照组21例。 2组均予常规康复训练与物理治疗，iTBS组增加对小脑蚓部的iTBS治疗，治疗2周。2组分别在治疗前后 进行下肢Fulg-Meyer量表（Fugl-Meyer assessment of Lower erxtremity，FMA-LE）、6 min步行测试、60°/s 向 心伸膝肌力测定、Berg 平衡量表（Berg balance scale，BBS）、改良 Ashworth 量表（modified Ashworth scale， MAS）、Barthel指数（Barthel index，BI）的评定。结果：治疗前2组患者的FMA-LE、6 min步行测试、60°/s 向 心伸膝肌力测定、BBS、MAS、BI评分差异均无统计学意义（P＞0.05）。治疗后2组患者的FMA-LE、6 min步 行测试、60°/s 向心伸膝肌力测定、BBS、MAS、BI评分均提高（P＜0.05），iTBS组的FMA-LE、60°/s 向心伸膝 肌力测定、BBS、BI评分优于对照组（P＜0.05）。结论：iTBS刺激小脑蚓部治疗能改善脑卒中患者下肢运动 功能障碍，提高日常生活活动能力。

To investigate the effects of intermittent theta short burst pulse stimulation (iTBS) to the cerebellum vermis on lower limb motor dysfunction in stroke patients. Methods: A total of 42 stroke patients with post-stroke lower limb motor dysfunction were randomly divided into an iTBS group (21 cases) and a control group (21 cases). Both groups underwent standard rehabilitation training and physical therapy, with the iTBS group also receiving targeted iTBS to the cerebellar vermis for two weeks. The Fugl-Meyer assessment of Lower erxtremity (FMA-LE), 6-minute walking test, 60°/s concentric knee extension strength measurement, Berg Balance Scale (BBS), Modified Ashworth Scale (MAS) and Barthel Index (BI) were assessed before and after treatment in both groups. Results: There were no statistically significant differences in the FMA-LE, 6-minute walking test, 60°/s concentric knee extension strength measurement, BBS, MAS or BI scores between the two groups before treatment (P>0.05). After treatment, both groups showed significant improvements in the scores for the FMA-LE, 6-minute walking test, 60°/s concentric knee extension strength measurement, BBS, MAS and BI (P<0.05), whereas the iTBS group exhibited superior improvements in the FMA-LE, 60°/s concentric knee extension strength measurement, BBS and BI scores compared to the control group (P<0.05). Conclusion: iTBS targeting the cerebellar vermis can improve lower limb motor function and daily living abilities in stroke patients.