目的：评估3D打印导板导航技术应用于三叉神经半月神经节射频热凝术（PRT）治疗三叉神经痛的 临床疗效。方法：选取我院收治的原发性三叉神经痛、且有PRT指征的患者35例为研究对象，随机分为对 照组（15例）和观察组（20例）。对照组在数字减影血管造影（DSA）引导下行PRT，观察组用3D打印导板导 航辅助PRT。比较2组的一次穿刺成功率，经皮穿刺到达靶点所需时间，手术时长，DSA扫描次数，患者术 中不适，术后即刻、3 d、30 d的疼痛数字评分法（NRS）评分，术后1、3、6个月疗效评估，手术满意度，不良反 应及并发症发生率。结果：观察组的一次穿刺成功率高于对照组（P＜0.01）；观察组的穿刺到达靶点时间、 手术时长、DSA扫描次数、术中不适、术后不良反应、术后即刻、术后3 d NRS评分均低于对照组（P＜0.01）； 观察组术后不良反应发生率明显低于对照组（P＜0.01）。2组术后1个月的NRS评分、术后1、3、6月疗效评 估、满意度、二次手术差异无统计学意义（P＞0.05）。结论：3D打印导板导航技术辅助PRT有助于增加三叉 神经痛手术的高效性、安全性，减少疼痛及不良反应，有良好临床应用前景。

To evaluate the clinical efficacy of 3D printed guide plate navigation technology in the application of percutaneous radiofrequency thermocoagulation (PRT) for the treatment of trigeminal neuralgia. Methods: A total of 35 patients with primary trigeminal neuralgia and indications for PRT treated in our hospital were selected as research subjects and randomly divided into a control group (15 cases) and an observation group (20 cases). The control group underwent PRT guided by digital subtraction angiography (DSA), while the observation group used 3D printed guide plate navigation-assisted PRT. The two groups were compared in terms of the success rate of one-time puncture, the time required for percutaneous puncture to reach the target, operation duration, number of DSA scans, intraoperative discomfort in patients, Numerical Rating Scale (NRS) scores immediately after surgery, at 3 days, and at 30 days post-surgery, therapeutic effect evaluation at 1, 3, and 6 months after surgery, surgical satisfaction, adverse reactions, and the incidence of complications. Results: The success rate of one-time puncture in the observation group was higher than that in the control group (P<0.01); the observation group had lower times for puncture to reach the target, operation duration, number of DSA scans, intraoperative discomfort, adverse reactions after surgery, and NRS scores immediately after surgery and at 3 days post-surgery than the control group (P<0.01); the incidence of adverse reactions after surgery in the observation group was significantly lower than that in the control group (P<0.01). There was no statistically significant difference between the two groups in NRS scores at 1 month after surgery, therapeutic effect evaluation at 1, 3, and 6 months after surgery, satisfaction, and secondary surgeries (P>0.05). Conclusion: 3D printed guide plate navigation technology-assisted PRT helps increase the efficiency and safety of the surgery for trigeminal neuralgia, reduce pain and adverse reactions, and has a good prospect for clinical application.