目的：系统评价有氧运动对帕金森病患者认知功能的干预效果。方法：系统检索PubMed、Embase、 Web of Science、The Cochrane Library、PsycINFO、中国知网数据库、万方数据库、维普数据库、中国生物医学 文摘数据库，收集从建库至2022年5月22日公开发表的有氧运动干预帕金森病患者认知功能的随机对照 试验和非随机对照试验。进行文献筛选、数据提取和质量评价后，采用Stata17.0软件进行Meta分析。结 果：共纳入19项研究，Meta 分析结果显示，与对照组比较，有氧运动可提高帕金森病患者的注意力（SMD= 0.31；95%CI 0.13～0.50；P＜0.001）、执行功能（SMD=0.59；95%CI 0.39～0.78；P＜0.001）、记忆力（SMD= 0.43；95%CI 0.09～0.77；P=0.02）评分。结论：有氧运动可以改善帕金森病患者的记忆力、执行功能和注意 力，但其具体的运动剂量仍需要更多高质量的研究进一步完善。

To evaluate the effect of aerobic exercise on cognitive function in patients with Parkinson’s disease. Methods: The literature was searched for randomized or non-randomized controlled trials on the effect of aerobic exercise on cognitive function in patients with Parkinson’s disease. Publications were then systematically retrieved from PubMed, Embase, Web of Science, The Cochrane Library, PsycINFO, China National Knowledge Internet, Wanfang, China Science and Technology Journal Database, and SinoMed from the date of database establishment to May 22, 2022. Meta-analysis was conducted using Stata 17.0 software after literature screening, data extraction, and quality evaluation. Results: A total of 19 studies were analyzed. Compared with the control group, patients with Parkinson’s disease who performed aerobic exercise showed significantly improved average scores of attention (SMD=0.31; 95% CI 0.13～0.50; P<0.001), executive function (SMD=0.59; 95% CI 0.39～0.78; P<0.001), and memory (SMD=0.43; 95% CI 0.09～0.77; P=0.02). Conclusion: Aerobic exercise can improve memory, executive function, and attention in patients with Parkinson's disease, but more high-quality studies are needed to determine the exact amount of exercise needed.