目的：探讨中青年脑卒中患者健康行为在残疾接受度和生活质量之间的中介作用。方法：选取2019 年7至2022年2月武汉市某三甲医院神经内科192例中青年脑卒中患者，采用一般资料调查表、残疾接受 度修订量表、健康促进生活方式量表、生活质量量表进行问卷调查。结果：中青年脑卒中患者残疾接受度 得分为（81.13±10.58）分，健康行为得分为（124.47±25.17）分，生活质量量表百分制总分为（59.59±10.52） 分。残疾接受度和健康行为均与生活质量呈正相关（P＜0.01）。健康行为在残疾接受度与生活质量间起 部分中介作用，中介效应占总效应的13.74%。结论：中青年脑卒中患者残疾接受度、健康行为和生活质量 均处于中等水平，健康行为可在残疾接受度和生活质量之间起部分中介作用。

To explore mediating role of health behaviors between disability acceptance and quality of life in young and middle-aged stroke patients. Methods: From July 2019 to February 2022, 192 cases of young and middle-aged stroke inpatients from the Department of Neurology of a tertiary care hospital in Wuhan were selected. Questionnaires were conducted using the general information questionnaire, Acceptance of Disability Scale-Revised (ADS-R), Health Promoting Lifestyle Profile Ⅱ (HPLP Ⅱ), and World Health Organization Quality of Life-BREF (WHOQOL-BREF). Results: The ADS-R score was (81.13 ± 10.58), the HPLP Ⅱ score was (124.47 ± 25.17), and the WHOQOL-BREF percentile score was (59.59 ± 10.52). Correlation analysis showed that both disability acceptance and health-promoting lifestyles were positively associated with quality of life (P<0.01). The mediating effect of health behaviors between disability acceptance and quality of life accounted for 13.74% of the total effect. Conclusion: Disability acceptance, health-promoting lifestyle, and quality of life are all moderate in young and middle-aged stroke patients. Health-promoting behavior plays a partially mediating role between disability acceptance and quality of life.