经颅磁刺激可作为一项无创的、非侵入性的测量大脑皮质兴奋性的神经生理技术，近年来广泛应用 于研究癫痫的病因及耐药机制等。本文对单/双脉冲经颅磁刺激在癫痫患者皮质兴奋性检测中的应用进行 综述，总结此项检测获得的参数在癫痫病因探索、癫痫分类及用药指导等方面的作用及前景。

Transcranial magnetic stimulation (TMS), as a non-invasive neurophysiological technique to measure cerebral cortical excitability, has been widely used to study the etiology and drug resistance mechanism of epilepsy in recent years. This article reviews the application of single/paired pulse TMS in detection of cortical excitability in patients with epilepsy, and summarizes the role of TMS in exploration of causes, classification and medication guidance of epilepsy.