目的：调查新型冠状病毒肺炎期间，在岗的护理人员创伤后应激障碍（PTSD）现状，并对相关影响因 素进行分析。方法：2020年5月至6月，使用自设的一般人口资料问卷、PTSD量表-民用版（PCL-C）对新冠 肺炎疫情期间在岗的3762名护理人员进行统计调查，并对一线与非一线护理人员占比差异进行对照分 析。结果：被调查的3762名护理人员中，PCL-C总得分均分（42.18±16.85）分，PTSD筛查阳性率达53.8%。 条件Logistic回归分析发现，PTSD的危险因素包括高行政职称、无职务、工作年限较低、月收入低、有子女、 非一线护理人员。对照研究发现，月收入越高、月夜班数超过2天、在三级医院工作、以前参与过灾害救援 的护理人员中一线工作者占比更高。结论：疫情期间在岗护理人员普遍存在一定程度的PTSD，相关部门 管理者应充分给予重视，及时采取针对性干预措施。

To investigate post-traumatic stress disorder (PTSD) in in-serviced nurses during COVID-19, and analyze the influencing factors. Methods: From May to June 2020, a self-designed general population data questionnaire and the PTSD Checklist–Civilian Version (PCL-C) were used to investigate 3762 nurses on duty during COVID-19, and make a comparative analysis of the difference between front-line and non-front-line nursing. Results: Among the 3762 nurses surveyed, the average PCL-C score was (42.18 ± 16.85), and the positivity rate of PTSD screening was 53.8%. Logistic regression analysis showed that the risk factors of PTSD included high administrative title, lack of post, fewer working years, low income, having children, and being non-front-line nurses. The control study showed that there were more front-line nurses in those who had higher incomes, worked more than two night shifts per month, worked in tertiary hospitals, and participated in disaster relief before. Conclusion: PTSD exists commonly in on-the-job nurses during COVID-19. Managers should pay full attention to those affected and take targeted and timely intervention measures.