摘要
目的:分析镜像后交通动脉瘤的形态学指标以评估动脉瘤破裂风险。方法:回顾性分析39对破裂的
镜像后交通动脉瘤的形态学参数,将以下参数纳入条件Logistic回归:动脉瘤高度、宽度、颈宽、尺寸比、纵横
比、宽/颈比、高/宽比、颈内动脉直径、是否有子瘤及动脉瘤高度>宽度。将单因素分析中与破裂有显著相关
(P<0.05)的参数纳入多因素回归分析。在本中心的 434 例后交通动脉瘤患者中使用受试者特征曲线
(ROC)和曲线下面积(AUC)检验独立危险因素的预测敏感性和特异性。结果:动脉瘤有子瘤(OR=8.852,
P=0.024)、动脉瘤高度>宽度(OR=18.250,P=0.011)和动脉瘤宽度(OR=1.645,P=0.024)是后交通动脉瘤破裂
的独立危险因素,其AUC值分别为0.737、0.761及0.686。结论:动脉瘤宽度、动脉瘤高度>宽度和有子瘤可
能是后交通动脉瘤破裂的形态学独立危险因素;其中子瘤形成是评估后交通动脉瘤破裂风险的最佳因素。
Abstract
To assess the risk of rupture using morphological parameters of mirror posterior communicating artery (PcoA) aneurysms. Methods: We retrospectively analyzed the morphological parameters of 39
pairs of ruptured mirror PcoA aneurysms. We performed conditional univariate and multivariate logistic regression for the following morphological parameters: aneurysm height, width, neck width, size ratio, aspect ratio, bottle/neck factor, height/width ratio, internal carotid artery diameter, daughter sac presence and whether height >
width. Multivariate regression analysis was performed on the factors found by univariate analysis to have significant correlation with aneurysm rupture (P<0.05). We used receiver operating characteristics (ROC) and the area
under the curve (AUC) to test the predictive accuracy of the independent factors for 434 PcoA aneurysm cases in
our database. Results: Presence of a daughter sac (OR=8.852, P=0.024), aneurysm with height > width (OR=
18.250, P=0.011), and aneurysm width (OR=1.645, P=0.024), were independent risk factors for the rupture of
PcoA aneurysms. The AUC of these factors were 0.737, 0.761, and 0.686, respectively. Conclusion: Aneurysm
width, aneurysm with height > width, and daughter sac presence may be independent risk factors for the rupture
of PcoA aneurysms. Among these, daughter sac presence was the most accurate predictor for rupture.
关键词
后交通动脉动脉瘤 /
镜像动脉瘤 /
破裂 /
形态学参数 /
危险因素
Key words
posterior communicating artery aneurysm
胡胜旗;徐伟东;厉华;陈如东.
镜像后交通动脉瘤破裂的形态学危险因素分析[J]. 神经损伤与功能重建. 2022, 17(10): 575-578
Morphological Evaluation of Risk of Mirror Posterior Communicating Artery Aneurysm Rup?
ture[J]. Neural Injury and Functional Reconstruction. 2022, 17(10): 575-578
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