微血管减压术后疱疹病毒感染的临床特征分析

张琪 ;陈浩 ;张作慧 ;陈雪婷 ;郑惠文 ;刘洁 ;Hafiz Khuram Raza ;昝坤 ;张沈阳 ;王钰乔 ;张尊胜

神经损伤与功能重建 ›› 2021, Vol. 16 ›› Issue (4) : 199-201.

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神经损伤与功能重建 ›› 2021, Vol. 16 ›› Issue (4) : 199-201.
论著

微血管减压术后疱疹病毒感染的临床特征分析

  • 张琪1 ,陈浩2 ,张作慧2 ,陈雪婷1 ,郑惠文1 ,刘洁1 ,Hafiz Khuram Raza1 ,昝坤2 ,张沈阳2 ,王钰乔2 ,张尊胜2
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Clinical Characteristics of Herpes Virus Infection after Microvascular Decompression

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摘要

目的:探讨微血管减压术后疱疹病毒感染的临床特征、治疗及预后,以提高临床医生对此病的认识。 方法:报道2例微血管减压术后疱疹病毒感染患者的临床资料并结合相关文献进行回顾性分析。结果:既 往文献共有7例符合纳入标准,加上本文报道的2例,共9例患者。其中5例为水痘带状疱疹病毒感染,3例 为单纯疱疹病毒感染,1例病毒类型不明。6例原发病为三叉神经痛,3例为面肌痉挛。其最常见症状为面 部疱疹(5例),部分患者出现不典型症状如发热头痛(4例)、眼结膜炎(1例)、面瘫(1例)、面肌痉挛(1例)。 经阿昔洛韦抗病毒后所有患者临床症状均好转,且预后较好。结论:微血管减压术后如出现发热、面部疼 痛、面肌痉挛、面瘫、眼部症状时,需考虑有无疱疹感染可能,确诊后需及时抗病毒治疗。

Abstract

To analyze the clinical features, treatment, and prognosis of patients with herpes virus infection after microvascular decompression. Methods:We reported the clinical data of 2 patients with herpes virus infection after microvascular decompression and retrospectively analyzed the relevant literature. Results: A literature search revealed 7 previous cases fulfilling the criteria of this study. We combined these 7 cases with our 2 and analyzed a total of 9 cases. Among them, 5 were infected by the varicella-zoster virus, 3 by the herpes simplex virus, and 1 by an unidentified virus; 6 cases had primary trigeminal neuralgia, and 3 had hemifacial spasm. The most common symptom was facial herpes (5 cases). Some patients developed atypical symptoms such as fever and headache (4 cases), ocular conjunctivitis (1 case), facial paralysis (1 case), and facial muscle spasm (1 case). All the patients were given acyclovir for antiviral treatment; clinical symptoms were subsequently improved, and prognosis was good. Conclusion:The clinical features of fever, facial pain, facial muscle spasm, facial paralysis, and ocular symptoms after microvascular decompression may indicate herpes virus infection. Physicians should closely monitor the patients’skin for the presence of herpes, perform serological or cerebrospinal fluid virus testing when necessary, and administer antiviral treatment in a timely manner.

关键词

微血管减压术 / 疱疹病毒 / 三叉神经痛 / 面肌痉挛 / 脑炎

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microvascular decompression

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张琪 ;陈浩 ;张作慧 ;陈雪婷 ;郑惠文 ;刘洁 ;Hafiz Khuram Raza ;昝坤 ;张沈阳 ;王钰乔 ;张尊胜. 微血管减压术后疱疹病毒感染的临床特征分析[J]. 神经损伤与功能重建. 2021, 16(4): 199-201
Clinical Characteristics of Herpes Virus Infection after Microvascular Decompression[J]. Neural Injury and Functional Reconstruction. 2021, 16(4): 199-201

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