目的：了解武汉市新型冠状病毒肺炎定点医院护士焦虑抑郁情绪现状。方法：采用横断面调查的研究 设计，使用患者健康问卷（PHQ-9）和广泛性焦虑障碍量表（GAD-7），了解武汉某定点医院护士的焦虑抑郁情 绪现状。结果：定点医院护士抑郁检出率为35.4%，焦虑检出率为33.6%。一线护士和非一线护士焦虑抑郁 情绪检出率差异无统计学意义（P>0.05）；护士焦虑抑郁情绪受性别、年龄、婚姻状态、与新冠肺炎患者接触、 同事感染和自身相关症状等因素的影响。讨论：武汉市新型冠状病毒肺炎定点医院包括一线和非一线护士 均存在明显焦虑抑郁情绪。

To analyze the current state of anxiety and depression among nurses in designated hospitals for novel coronavirus pneumonia and analyze its causes and propose countermeasures. Methods: A cross-sectional study design was used to evaluate the current state of anxiety and depression among nurses in a designated hospital in Wuhan by using the 9-item patient health questionnaire (PHQ-9) and the 7-item generalized anxiety disorder scale (GHD-7). Results: Within this hospital, 35.4% of nurses have depression symptoms and 33.6% have anxiety symptoms. There was no statistical difference in the detection rate of anxiety and depression between frontline nurses and non-frontline nurses, as non-frontline nurses also showed significant anxiety and depression. The anxiety and depression experienced by nurses were affected by gender, age, marital status, contact with patients with novel coronavirus pneumonia, infection in colleagues, and their own relevant symptoms. Conclusion: The nurses in the designated hospital for novel coronavirus pneumonia in Wuhan, including both frontline and non-frontline nurses, suffer apparent anxiety and depression. Hospitals should establish an emergency psychological intervention system to carry out extensive preventive psychological intervention and strengthen training in infection-related knowledge and skills to relieve nurses' anxiety and depression.