目的：分析硝唑类脑病的特点及预后。方法：收集2例硝唑类脑病患者的临床资料，并搜集相关文献 进行回顾性分析。结果：2例患者均表现为急性亚急性起病的小脑神经系统缺损症状；MRI显示损伤部位1 例为胼胝体和小脑齿状核，1例为齿状核；停药后症状均迅速好转。检索文献获得硝唑类脑病患者69例临 床资料，亚裔人为41例，首发临床症状中小脑功能缺损为 62例，MRI累积部位齿状核63例，患者临床症状 完全恢复65例。结论：硝唑类脑病多累及小脑、胼胝体及脑干，尤以亚裔人多发，预后相对较好。

To analyze the characteristics and prognosis of nitroimidazole encephalopathy. Methods: The clinical data of 2 patients with nitroimidazole encephalopathy were collected, and relevant literatures were collected for retrospective analysis. Results: The 2 patients both showed symptoms of cerebellar nervous system defect in acute or subacute onset. MRI revealed injury location to be the corpus callosum in 1 case and cerebellar dentate nucleus in the other case. Symptoms in both cases rapidly improved after stopping drug use. Literature analysis showed that, among a total of 69 patients, 41 cases were Asian, 62 cases experienced cerebellar dysfunction among first clinical symptoms, 63 cases displayed an MRI accumulation site at the dentate nucleus, and 65 cases demonstrated a complete recovery of clinical symptoms. Conclusion: Nitroimidazole encephalopathy involves the cerebellum, corpus callosum, and brainstem, is more prevalent in Asians, and shows relatively good prognosis.