摘要
目的:探讨SOAR和ASTRAL评分对急性缺血性卒中(AIS)患者1年不良预后的预测价值。方法:纳 入AIS患者807例,收集临床基线资料,同时应用SOAR和ASTRAL量表进行评分,并进行1年随访。以患
者1年时出现死亡或功能残障(mRS≥3分)作为不良结局事件。通过受试者工作特征曲线下面积(AUC)比 较 2 个量表的预测价值。结果:最终纳入 AIS 患者 772 例进行数据分析,1 年随访出现不良结局 196 例 (25.4%),其中死亡68例(8.8%)。SOAR和ASTRAL量表预测AIS患者1年不良预后结局的AUC值分别为
0.739和0.860(均P<0.001),差异有统计学意义(P<0.001);SOAR和ASTRAL量表预测AIS患者1年死亡
结局的AUC值分别为0.755和0.809,差异有统计学意义(P<0.001)。结论:应用SOAR和ASTRAL量表能
够较好地对AIS人群的1年不良预后进行预测;ASTRAL量表的预测能力优于SOAR量表。
Abstract
To investigate the predictive value of SOAR and ASTRAL scores for one-year poor
prognosis in patients with acute ischemic stroke (AIS). Methods: A total of 807 AIS patients were enrolled.
Clinical baseline data were collected and scored with SOAR and ASTRAL scores. A prospective cohort
follow-up study was performed for 1 year. The patient had a death or functional disability at 1 year [modified
Rankin score (mRS) ≥3 points] as an adverse outcome event. The area under the receiver operating
characteristic curve (AUC) was used to compare the predicted values of the two scales. Results: A total of 772
AIS patients' data were collected in the study. There were 196 (25.4% ) adverse outcomes at 1 year follow-up,
including 68 deaths (8.8%). The AUR values for the 1-year adverse outcome of the AIS patients predicted by the
SOAR and ASTRAL scales were 0.739, 0.860, respectively (both P<0.001). Further comparisons were made
between the two scales, the difference was statistically significant (P<0.001). The 1 year mortality outcome of
AIS patients was further analyzed by two scales. The AUC values were 0.755, 0.809 (both P<0.001). Further
comparison between the two groups was statistically significant (P<0.001). Conclusion: The SOAR and
ASTRAL scales can predict the 1-year adverse prognosis of AIS population. The ASTRAL scale is superior to
SOAR scale in predicting 1-year adverse outcomes and death events in patients with AIS.
关键词
急性缺血性卒中 /
不良预后 /
SOAR量表 /
ASTRAL量表
Key words
acute ischemic stroke
高金颖a
;胡蓉
;金迪b
;张绿明b
;赵静b
;马瑞b
;邱石b.
SOAR量表和ASTRAL量表评分对急性缺血性卒中患者1年不良预后的预测功能评价[J]. 神经损伤与功能重建. 2019, 14(8): 383-385
Comparison of the SOAR Score and ASTRAL Score in 1 Year Poor Prognosis in Patients with
Acute Ischemic Stroke[J]. Neural Injury and Functional Reconstruction. 2019, 14(8): 383-385
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