神经退行性疾病是由神经元和（或）其髓鞘丧失所致神经系统的结构损害，随着时间推移逐渐恶化， 随之出现功能障碍的一类疾病。脑磁图（magnetoencephalography，MEG）是对脑组织自发的神经磁场的记 录，是一种完全无侵袭、无损害的脑功能检测技术，具有良好的时间和空间分辨率，已逐渐应用于神经退行 性疾病的早期诊断中。本文主要描述MEG在阿尔茨海默病、帕金森病、多发性硬化、路易体痴呆、额颞叶 痴呆、肌萎缩侧索硬化症等神经系统退行性疾病的临床应用。

Neurodegenerative diseases are structural damage to the nervous system caused by the loss of neurons and/or their myelin sheaths, which progressively worsens over time, leading to dysfunction. Magnetoencephalography (MEG) is a record of the spontaneous neural magnetic field of brain tissue, which is a completely non-invasive and non-damaging brain function detection technology with good temporal and spatial resolution, and has been gradually applied to the early diagnosis of neurodegenerative diseases. This review mainly describes the clinical application of MEG in neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, Multiple sclerosis, Dementia with Lewy bodies, Frontotemporal dementia and Amyotrophic lateral sclerosis.