多种干预措施治疗帕金森病后吞咽障碍的网状meta分析

杨媛媛1 ,杜锦超2 ,雷俊芳3 ,周珊珊1 ,冯露叶1 ,汤继芹1

神经损伤与功能重建 ›› 2026, Vol. 21 ›› Issue (1) : 7-12.

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神经损伤与功能重建 ›› 2026, Vol. 21 ›› Issue (1) : 7-12.
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多种干预措施治疗帕金森病后吞咽障碍的网状meta分析

  • 杨媛媛1 ,杜锦超2 ,雷俊芳3 ,周珊珊1 ,冯露叶1 ,汤继芹1
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A Network Meta-analysis of Multiple Interventions for the Treatment of Dysphagia afterParkinson's Disease

  • YANG Yuanyuan1 ,DU Jinchao2 ,LEI Junfang3 ,ZHOU Shan-shan1 ,FENG Luye1 ,TANG Ji-qin1
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摘要

目的:系统评价多种干预措施对帕金森病患者吞咽功能的改善效果。方法:检索 CNKI、Wanfang、 VIP、CBM、PubMed、Medline和Web of science数据库,搜集关于不同治疗方法治疗帕金森病患者吞咽障碍 的RCTs,时段为建库至2024年3月15日。利用RevMan 5.4.1软件评估纳入研究的质量,Stata 17.0软件进 行网状Meta分析。结果:纳入研究29篇,1 870例患者,涉及针刺、电刺激、呼吸训练等13种治疗方法。网状 Meta分析结果显示,在提高帕金森病临床有效率及PAS方面,训练效果最好的是呼吸训练;提高SSA、洼田 饮水评分方面,重复经颅磁刺激与电刺激效果最好。结论:现有证据表明,呼吸训练成为治疗帕金森病吞咽 障碍最佳干预方案的可能性最大,重复经颅磁刺激与电刺激也具有一定优势。

Abstract

To systematically evaluate the effect of various interventions on the improvement of swallowing function in patients with Parkinson's disease. Methods: CNKI, Wanfang, VIP, CBM, PubMed, Medline and Web of science databases were searched to collect RCTs on different treatment methods for dysphagia in Parkinson's patients from inception to March 15, 2024. RevMan 5.4.1 software was used to evaluate the quality of the included studies, and Stata 17.0 software was used for network meta-analysis. Results: A total of 29 studies involving 1 870 patients were included, involving 13 treatment methods such as acupuncture, electrical stimulation, and respiratory training. The results of network meta-analysis showed that the best training effect was respiratory training in improving the clinical efficiency and PAS of Parkinson's disease. In terms of improving SSA and Kubota drinking water scores, repetitive transcranial magnetic stimulation and electrical stimulation have the best effect. Conclusion: The existing evidence shows that respiratory training is the most likely to be the best intervention for Parkinson's dysphagia. Repetitive transcranial magnetic stimulation and electrical stimulation also have certain advantages.

关键词

帕金森病;吞咽障碍;干预措施;网状Meta分析

Key words

Parkinson's disease; dysphagia; interventions; Network Meta-analysis

引用本文

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杨媛媛1 ,杜锦超2 ,雷俊芳3 ,周珊珊1 ,冯露叶1 ,汤继芹1. 多种干预措施治疗帕金森病后吞咽障碍的网状meta分析[J]. 神经损伤与功能重建. 2026, 21(1): 7-12
YANG Yuanyuan1 ,DU Jinchao2 ,LEI Junfang3 ,ZHOU Shan-shan1 ,FENG Luye1 ,TANG Ji-qin1. A Network Meta-analysis of Multiple Interventions for the Treatment of Dysphagia afterParkinson's Disease[J]. Neural Injury and Functional Reconstruction. 2026, 21(1): 7-12

基金

山东中医药大学科 研创新团队基金资 助项目(经方治疗 重大疾病作用机理 与疗效评价科研创 新团队,No. 22031 6);山东省高等学 校 科 技 计 划 项 目 (针刺配合康复训 练治疗脑中风后吞 咽 障 碍 的 循 证 研 究,No. J14LK08)

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