Theta爆发式磁刺激治疗脑卒中后认知障碍的研究进展

赵若璇1,2 ,彭彦霞2 ,张林丽1,2 ,王承烁1,2 ,祁婧曼1,2 ,项奥梦1,2 ,付艳鑫1,2 ,武亮2

神经损伤与功能重建 ›› 2026, Vol. 21 ›› Issue (1) : 20-23.

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神经损伤与功能重建 ›› 2026, Vol. 21 ›› Issue (1) : 20-23.
综述

Theta爆发式磁刺激治疗脑卒中后认知障碍的研究进展

  • 赵若璇1,2 ,彭彦霞2 ,张林丽1,2 ,王承烁1,2 ,祁婧曼1,2 ,项奥梦1,2 ,付艳鑫1,2 ,武亮2
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Research Progress of Theta Burst Stimulation in the Treatment of Post-Stroke CognitiveImpairment

  • ZHAO Ruoxuan1,2 ,PENG Yanxia2 ,ZHANG Linli1,2 ,WANG Chengshuo1,2 ,QI Jingman1,2 ,XIANG Aomeng1,2 ,FU Yanxin1,2 ,WU Liang2
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摘要

脑卒中后认知障碍(Post-stroke cognitive impairment,PSCI)是脑卒中的一种常见并发症,严重影响卒中 患者的日常生活、工作和社会交往。Theta爆发式磁刺激(Theta burst stimulation,TBS)是一种特殊的重复经颅 磁刺激(repetitive transcranial magnetic stimulation,rTMS)模式,相比传统rTMS具有应用时间短、耐受性更好、 治疗效果持久等优势,能够诱导大脑皮质产生持续性兴奋性变化,在PSCI治疗中的研究日益增多,其疗效在 临床研究中得到证实。本研究重点总结TBS在脑卒中后注意力、语言、执行、记忆这4个认知康复领域中的研 究进展,并梳理和整合TBS治疗PSCI的作用机制,为TBS治疗PSCI研究的深入开展提供借鉴和参考。

Abstract

Post-stroke cognitive impairment (PSCI) is a common complication of stroke, which seriously affects the daily life, work and social interaction of stroke patients. Theta burst stimulation (TBS) is a special repetitive transcranial magnetic stimulation (rTMS) mode. Compared with traditional rTMS, TBS has the advantages of short application time, better tolerance and lasting therapeutic effect, and can induce persistent excitatory changes in the cerebral cortex. More and more studies have been conducted in the treatment of PSCI, and its efficacy has been confirmed in clinical studies. This study focuses on summarizing the research progress of TBS in the four cognitive rehabilitation fields of attention, language, executive, and memory after stroke, and combing and integrating the mechanism of action of TBS in the treatment of PSCI, so as to provide reference for the further development of TBS treatment of PSCI.

关键词

脑卒中;认知障碍;Theta爆发式磁刺激;综述

Key words

stroke; cognitive impairment; Theta burst stimulation; review

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赵若璇1,2 ,彭彦霞2 ,张林丽1,2 ,王承烁1,2 ,祁婧曼1,2 ,项奥梦1,2 ,付艳鑫1,2 ,武亮2. Theta爆发式磁刺激治疗脑卒中后认知障碍的研究进展[J]. 神经损伤与功能重建. 2026, 21(1): 20-23
ZHAO Ruoxuan1,2 ,PENG Yanxia2 ,ZHANG Linli1,2 ,WANG Chengshuo1,2 ,QI Jingman1,2 ,XIANG Aomeng1,2 ,FU Yanxin1,2 ,WU Liang2. Research Progress of Theta Burst Stimulation in the Treatment of Post-Stroke CognitiveImpairment[J]. Neural Injury and Functional Reconstruction. 2026, 21(1): 20-23

基金

北京市属医院科 研培育项目(强 化对称负重式坐 站训练对脑卒中 偏瘫患者步行的 有效性和安全性 的影响,PX2024 075);首都卫生 发展科研专项项 目(早期高频重 复经颅磁刺激对 脑卒中后手部感 觉障碍改善效果 的 研 究 ,首 发 2020-2-2201)

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