肠道微生物组是人体内最大的微生物库，在神经发育、衰老和脑部疾病中发挥着重要作用。近年来， 肠道菌群越与缺血性脑卒中的关系也成为脑卒中研究者的热门研究课题。在正常情况下，肠道微生物群与 人体和外部环境保持平衡状态，然而在高原地区，可能因缺氧导致消化功能紊乱致使细菌移位和肠道微生 物群失衡。本文就动脉粥样硬化性缺血性脑卒中与高原肠道菌群的相关性研究进行综述，同时对其治疗前 景进行展望。

The gut microbiome is the largest microbial reservoir in the human body and plays a significant role in neural development, aging, and brain diseases. In recent years, the relationship between gut microbiota and ischemic stroke has become a hot research topic among stroke researchers. Under normal circumstances, the gut microbiota maintains a balanced state with the human body and the external environment. However, in high-altitude regions, hypoxia may lead to digestive dysfunction, causing bacterial translocation and imbalance of the gut microbiota. This article provides an overview of the correlation between atherosclerotic ischemic stroke and plateau gut microbiota and looks forward to its therapeutic prospects.