目的：探讨神经导航及 C 臂辅助下经皮三叉神经微球囊压迫术（PBC）与显微镜下微血管减压术 （MVD）治疗三叉神经痛的疗效及安全性。方法：回顾性搜集我院收治的三叉神经痛患者144例的临床资 料，根据治疗方法分为MVD组67例和PBC组77例，分析、比较2组患者的术前因素、术后疗效及并发症、 住院时间、手术时长等数据。结果：PBC组患者年龄大于MVD组（P＜0.05）。2组患者在术后即刻、术后 6个月及术后1年时的疼痛缓解率差异无统计学意义（均P＞0.05）；对于年龄＞60岁的患者，PBC治疗后的 疼痛缓解率显著高于MVD（P＜0.05）。2组手术并发症存在差异，MVD组眩晕发生率为60.0%，明显高于 PBC组（P＜0.05）；PBC组面部麻木（52.6%）、咀嚼肌无力（40.2%）和疱疹（7.79%）的发生率明显高于MVD 组（P＜0.05）。PBC组的手术时长和住院天数均显著低于MVD组（P＜0.05）。结论：PBC和MVD治疗三叉 神经痛的总体疗效相似，并发症存在差异，老年患者更适合选择PBC治疗。

To explore the safety and efficacy of neuronavigation and C-arm-assisted percutaneous balloon compression (PBC) and microvascular decompression (MVD) in treating trigeminal neuralgia. Meth? ods: Clinical data of 144 patients treated for trigeminal neuralgia at our hospital were retrospectively collected. Patients were divided into the MVD group (n=76) and PBC group (n=77) based on method of treatment. Preoperative factors, postoperative efficacy and complications, length of hospitalization, and duration of operation were analyzed and compared between the two groups. Results: The patients in PBC group were older than the patients MVD group (P<0.05). There was no statistical difference in the pain relief rate of the two groups immediately, 6 months, and 1 year after surgery (all P>0.05). In patients aged>60, the postoperative pain relief rate after PBC was higher than that after MVD (P<0.05). The two groups showed differences in postoperative complication. The incidence of vertigo was 60.0% in the MVD group, significantly higher than that in the PBC group (P<0.05). In the PBC group, the incidence of facial numbness (52.6% ), masticatory muscle disorder (40.2% ), and herpes (7.79%) were significantly higher than those in the MVD group (all P<0.05). Operation time and hospitalization time were both significantly lower in the PBC group compared to the MVD group (all P<0.05). Con? clusion: PBC and MVD show similar efficacy in the treatment of trigeminal neuralgia but show differences in postoperative complications. In the elderly, PBC is the more suitable procedure.