摘要
目的:探讨脊髓前动脉综合征(ASAS)的临床特点、MRI特点、病因和预后,提高医师对脊髓梗死的认
识。方法:回顾1例ASAS患者的临床特点、MRI特点及治疗和预后,并结合文献进行回顾性分析。结果:患
者临床表现为急性起病,后背疼痛,双下肢瘫,痛温觉障碍,深感觉和触觉正常,尿潴留及排便障碍,MRI检
查弥散序列显示T7-8、T11-12水平脊髓横断前部区域呈高信号影,稍长T2信号,综合治疗后预后良好。搜索既
往报道的ASAS患者207例,临床表现特征是急性或亚急性起病,病变水平神经根痛,病变节段以下瘫痪和
分离性感觉障碍及植物神经功能障碍,以胸段脊髓梗死多见,发病早期MRI弥散序列检查可显示脊髓梗死
范围。207例患者中,病因不明者74例(35.8%)。颈部外伤是年龄<18岁患者脊髓梗死的首位病因;主动脉
疾病是年龄18~45岁患者脊髓梗死的首位病因,动脉粥样硬化是年龄>45岁患者脊髓梗死的首位病因。
结论:ASAS较罕见,临床表现和病因差异很大,脊髓MRI检查弥散序列有助早期诊断,早期诊断和综合治
疗是改善预后的关键
Abstract
To explore the clinical features, MRI features, cause, and prognosis of anterior spinal
artery syndrome (ASAS) and improve the understanding of spinal cord infarction. Methods: The clinical
features, MRI characteristics, treatment, and prognosis of 1 case of ASAS were retrospectively analyzed, and the
relevant literature was reviewed. Results: The patient displayed acute onset of illness, back pain, paraplegia,
thermal and pain sensory disorder, normal deep sense and tactile sense, urine retention, and fecal elimination
disorder. MRI with DWI sequence showed hyperintensities at the T7-8 and T11-12 levels within the anterior portion
of the spinal cord transection and slightly elevated T2 signals. Comprehensive treatment was adopted, and the
patient had a good prognosis. We collected the data of 207 cases of ASAS. Most patients presented with acute or
subacute onset, nerve root pain, paraplegia, dissociative sensory disorder, and autonomic nerve function disorder.
Thoracic spinal cord infarction is most common. In early disease stages, DWI is able to detect regions of spinal
cord infarction. Of the 207 patients, 74 (35.8% ) had unknown etiology. In patients under 18 years old, neck
trauma was the primary cause of spinal cord infarction. In patients aged 18 to 45 years, aortic disease was the
primary cause of spinal cord infarction. In patients over 45 years old, atherosclerosis was the primary cause of
spinal cord infarction. Conclusion: ASAS is rare, and its clinical manifestations and etiologies vary greatly. The
diffuse sequence of MRI is helpful for early diagnosis. Early diagnosis and comprehensive treatment is the key to
improving prognosis
关键词
脊髓梗死 /
脊髓前动脉综合征 /
脊髓前动脉梗死 /
临床特征 /
磁共振成像
Key words
spinal cord infarction
康健捷a
;邓兵梅a
;杨红军a
;彭凯润a
;王伟民b.
脊髓前动脉综合征1例报道并文献复习[J]. 神经损伤与功能重建. 2018, 13(6): 284-288
Analysis of Clinical Characteristics of Anterior Spinal Artery Syndrome: Case Report and
Literature Review[J]. Neural Injury and Functional Reconstruction. 2018, 13(6): 284-288
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