针刺治疗功能性消化不良患者焦虑抑郁情绪:一项系统评价和Meta分析

孙颖哲1 ,姜盛文4 ,高扬3 ,刘关平2 ,范程欣2 ,孙远征2 ,于天洋2

神经损伤与功能重建 ›› 2026, Vol. 21 ›› Issue (7) : 393-399.

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中国科技核心期刊
美国《化学文摘》CAS数据库收录
日本科学技术振兴机构数据库收录
湖北省优秀期刊
中国知网网络首发期刊
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神经损伤与功能重建 ›› 2026, Vol. 21 ›› Issue (7) : 393-399. DOI: 10.16780/j.cnki.sjssgncj.20240977
论著

针刺治疗功能性消化不良患者焦虑抑郁情绪:一项系统评价和Meta分析

  • 孙颖哲1 ,姜盛文4 ,高扬3 ,刘关平2 ,范程欣2 ,孙远征2 ,于天洋2
作者信息 +

Acupuncture for the Treatment of Anxiety and Depression in Functional Dyspepsia: ASystematic Review and Meta-Analysis

  • SUN Yingzhe1 ,JIANG Shengwen4 ,GAO Yang3 ,LIU Guanping2 ,FAN Chengxin2 ,SUN Yuanzheng2 ,YU Tianyang2
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摘要

目的:采用Meta分析评估针刺治疗功能性消化不良患者焦虑抑郁情绪的有效性。方法:自建库起至 2024年1月,检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普资讯中文期刊服务 平台(VIP)、中国生物医学文献服务系统(SinoMed)、PubMed、Web of Science、Embase 7个数据库收录的与 针刺治疗功能性消化不良患者焦虑抑郁情绪相关的随机对照研究文献。运用Revman 5.3、Stata 17.0对相 关结局指标进行分析。结果:总共纳入832例功能性消化不良患者(治疗组416例,对照组416例)。与对照 组相比,针刺能够改善治疗组患者的 SAS[MD=-0.55, 95%CI (-1.01, -0.10)]、SDS[MD=-1.18, 95%CI (-1.84, -0.52)]、HAMA[MD=-4.73, 95%CI (-11.59, 2.12)]、HAMD[MD=-4.35,95%CI (-9.15, 0.44)]、 HADS[MD=-3.01, 95%CI (-4.73, -1.29)]、消化不良症状积分[MD=-1.55, 95%CI (-2.04, -1.07)]、总 有效率[MD=2.62, 95%CI (1.70, 4.01)]。结论:针刺对于功能性消化不良患者的症状及焦虑抑郁情绪均具 有改善作用,但证据等级偏低。

Abstract

To evaluate the effectiveness of acupuncture in treating anxiety and depression in patients with functional dyspepsia (FD) through a meta-analysis. Methods: From database inception to January 2024, seven databases—CNKI, Wanfang, VIP, SinoMed, PubMed, Web of Science, and Embase—were searched for randomized controlled trials (RCTs) related to acupuncture for anxiety and depression in FD. Revman 5.3 and Stata 17.0 were used for outcome analysis. Results: A total of 832 FD patients were included (416 in the treatment group, 416 in the control group). Compared with the control group, acupuncture significantly improved SAS [MD=-0.55, 95% CI (-1.01, -0.10)], SDS [MD=-1.18, 95% CI (-1.84, -0.52)], HADS [MD=-3.01, 95% CI (-4.73, -1.29)], dyspepsia symptom score [MD=-1.55, 95% CI (-2.04, -1.07)], and total effective rate [MD= 2.62, 95% CI (1.70, 4.01)]. For HAMA [MD=-4.73, 95% CI (-11.59, 2.12)] and HAMD [MD=-4.35, 95% CI (-9.15, 0.44)], the differences were not statistically significant as the confidence intervals crossed zero. Conclusion: Acupuncture can improve both symptoms and anxiety/depression in patients with functional dyspepsia; however, the level of evidence remains low.

关键词

针刺;功能性消化不良;餐后不适综合征;上腹痛综合征;焦虑抑郁情绪;Meta分析

Key words

acupuncture; functional dyspepsia; postprandial distress syndrome; epigastric pain syndrome; anxiety and depressive mood; meta-analysis

引用本文

导出引用
孙颖哲1 ,姜盛文4 ,高扬3 ,刘关平2 ,范程欣2 ,孙远征2 ,于天洋2. 针刺治疗功能性消化不良患者焦虑抑郁情绪:一项系统评价和Meta分析[J]. 神经损伤与功能重建. 2026, 21(7): 393-399 https://doi.org/10.16780/j.cnki.sjssgncj.20240977
SUN Yingzhe1 ,JIANG Shengwen4 ,GAO Yang3 ,LIU Guanping2 ,FAN Chengxin2 ,SUN Yuanzheng2 ,YU Tianyang2. Acupuncture for the Treatment of Anxiety and Depression in Functional Dyspepsia: ASystematic Review and Meta-Analysis[J]. Neural Injury and Functional Reconstruction. 2026, 21(7): 393-399 https://doi.org/10.16780/j.cnki.sjssgncj.20240977

基金

黑龙江省博士后科 研 启 动 金(基 于 AMPK/SIRT1/PGC- 1a 通路研究头穴丛 刺对抑郁大鼠海马 神经元突触重塑的 影响,No. LBH-Q21 183);黑龙江中医 药大学校科研基金 (基于“少阳为枢” 理论针刺治疗抑郁 症的临床疗效评价 及对新靶点作用机 制研究,No. 2019M S21)

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